УДК 636.082.12:636.22/.28.033

https://doi.org/10.61562/mgfa2023.47

ПОЛИМОРФИЗМ ГЕНОВ GHR И IGF-1 У РЕМОНТНОГО МОЛОДНЯКА КАЗАХСКОЙ БЕЛОГОЛОВОЙ ПОРОДЫ
Суржикова Е.С.1, ЕвлагинаД.Д.2, ОнищенкоО.Н.2
1ВНИИОК – филиал ФГБНУ «Северо-Кавказский ФНАЦ», г. Ставрополь,
Российская Федерация
2ФГБОУ ВО «Ставропольский государственный аграрный университет»,
г. Ставрополь, Российская Федерация
e-mail: D1319731@yandex.ru
Abstract: It is known that meat productivity and meat quality in cattle are determined not only by paratypic, but also by genetic factors, therefore, the use of genetic markers is relevant and promising. The aim of the study was to determine gene polymorphism of growth hormone receptor (GHR) and insulin-like growth factor (IGF-1) and to carry out genetic and statistical analysis in a sample of young cattle (steers) of beef cattle of Kazakh white-headed breed. The allelic spectrum of the genes under study was determined by PCR-PDRF method. Research showed that in this sample of animals, the following genes were predominant: the GHRF allele and the GHRFF genotype of the growth hormone receptor gene; the IGF-1B allele and the IGF- 1ВB genotype of the insulin-like growth factor gene. Genetic equilibrium in the studied genes was observed in steers of Kazakh white-headed breed. It was also found that half of the animals (50.0 %) in the studied sample lacked complex genotypes with desirable alleles, while the rest of the sample was a carrier of three, two and one marker alleles of two genes.
Keywords: polymorphism; genotype; breed; somatotropinomas cascade; cattle; GHR; IGF-1